Bowling Green vs Louisville Prediction, Picks & Odds | 20 Sep 2025

College Football Betting Preview: Bowling Green vs Louisville

Bowling Green face Louisville in this NCAAF Week 4 matchup at L&N Federal Credit Union Stadium, with kickoff scheduled for 00:00 on Sunday 21 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Why Bowling Green Make Sense on the Spread

Bowling Green have been given a huge number on the spread. We recommend taking the 1.91 that they cover a more than generous +25.5 line against Louisville.

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Each Team Bidding to Secure Another Win

Bowling Green Falcons previous game saw them claim a 23-13 home win over Liberty Flames at Doyt L. Perry Stadium.

Louisville Cardinals last game was a 28-14 home win. This victory over James Madison Dukes at L&N Federal Credit Union Stadium made it back-to-back victories.

Quarterbacks

Drew Pyne

Miller Moss

Bowling Green vs Louisville Prediction & Picks

We’ve got your Bowling Green vs Louisville bets covered, including our expert match prediction, correct score recommendation and a hand-picked bet builder tailored for value.

Game Prediction

Let’s back Bowling Green at +25.5 to outrun their odds on the spread. They are a good shout at 1.91 to stay relatively close to the big favorites in this college football matchup.

Our CFB predictions are built after tracking the latest team news and reviewing recent form. We also dive into stats, which often serve as a solid barometer for how the action might unfold.

Key Bowling Green vs Louisville stats:

• The +25.5 line has been covered by Bowling Green in 20 consecutive games.
• The -25.5 line hasn’t been covered by Louisville in 15 of their last 20 games.
• The -25.5 line hasn’t been covered by Louisville in 7 of their last 10 games.

Bowling Green +25.5 Probability

When you look at the latest odds, our pick has a 52.4% chance of delivering a return. However, we have this figure at close to 60% based on our in-depth research. This is why we can recommend this college bet.

There’s the opportunity to sell points and that means moving the line until you’re happy with the bet. It means a riskier wager but a bigger return on the odds available.

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Correct Score Prediction

Bowling Green 20 - 41 Louisville

Should you want to go for a selection at massive odds, head to the correct score lines where Louisville can be backed speculatively to achieve a 41-20 victory.

Bowling Green vs Louisville Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Louisville Big Favorites to Win

The latest Moneyline betting odds give Louisville a 98% chance of winning this college game which means they’re overwhelming 1.02 favorites with the sportsbooks. For those wanting to back Bowling Green, you will find 17.00 about the underdogs.

The spread is 26.5 and the total points line is currently 50.5. There are many ways to wager on football including the Totals. Those who wager Under 50.5 can get 1.91.

Whether you are wagering pre-game or in-game on college football, the top betting apps let you feast on a wide range of team props and game lines. The selections are practically endless, and it’s awesome to have so many options at your fingertips.

Player Odds

Receiving Yards

Rushing Yards

Passing Yards

Can Louisville Keep Their Home Form Going?

Louisville have put together three straight wins at L&N Federal Credit Union Stadium. They have gone 7-3 across their last 10 home games, putting up 39.20 points on average and giving up 22.10.

Bowling Green have six wins and four losses in the last 10 games away from home, putting up 30.30 points per contest and giving up 22.50.

Last 10 Games		W-L	P	PF	PA	O51.5	U51.5
Louisville Home Stats		7-3	61.30	39.20	22.10	7	3
Bowling Green Away Stats		6-4	52.80	30.30	22.50	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O51.5 = Games Over 51.5 Points
• U51.5 = Games Under 51.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Bowling Green Falcons Stats

Louisville Cardinals Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +25.5 Betting Line: Have covered the spread in the last 10 games
• +25.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road

Point Spread

• -25.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -25.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 46.30 pts in the previous 10 games
• Game Totals on the Road: An average of 52.80 pts in the previous 10 games on the road
• Over 51.5: Covered in 3 of the previous 10 games
• Over 51.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 27.20 pts and allowed 19.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 30.30 pts and allowed 22.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 60.60 pts in the previous 10 games
• Game Totals at Home: An average of 61.30 pts in the previous 10 home games
• Over 51.5: Covered in 7 of the previous 10 games
• Over 51.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 36.00 pts and allowed 24.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 39.20 pts and allowed 22.10 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	W	L	PF	PA	N. Pts	Home	Away	Strk
California	3	0	96	32	64	2-0	1-0	3W
Florida State	2	0	108	20	88	2-0	0-0	2W
Georgia Tech	3	0	110	53	57	2-0	1-0	3W
Louisville	2	0	79	31	48	2-0	0-0	2W
Miami	3	0	121	39	82	3-0	0-0	3W
NC State	3	0	93	72	21	2-0	1-0	3W
Wake Forest	2	1	76	53	23	2-1	0-0	1L
Virginia	2	1	134	58	76	2-0	0-1	1W
SMU	2	1	115	71	44	1-1	1-0	1W
Syracuse	2	1	119	89	30	2-0	0-1	2W
Pittsburgh	2	1	130	57	73	2-0	0-1	1L
North Carolina	2	1	75	57	18	1-1	1-0	2W
Boston College	1	2	126	82	44	1-0	0-2	2L
Clemson	1	2	58	57	1	1-1	0-1	1L
Duke	1	2	91	96	-5	1-1	0-1	2L
Stanford	1	2	53	70	-17	1-0	0-2	1W
Virginia Tech	0	3	57	113	-56	0-2	0-1	3L

Mid-American	W	L	PF	PA	N. Pts	Home	Away	Strk
Bowling Green	2	1	69	54	15	2-0	0-1	1W
Buffalo	2	1	86	57	29	1-0	1-1	2W
Toledo	2	1	121	45	76	2-0	0-1	2W
Northern Illinois	1	1	28	37	-9	1-0	0-1	1L
Ball State	1	2	37	102	-65	1-0	0-2	1W
Central Michigan	1	2	36	122	-86	0-0	1-2	2L
Kent State	1	2	63	110	-47	1-1	0-1	2L
Ohio	1	2	57	81	-24	1-0	0-2	1L
Akron	0	3	28	109	-81	0-1	0-2	3L
Eastern Michigan	0	3	73	128	-55	0-1	0-2	3L
Massachusetts	0	3	43	116	-73	0-2	0-1	3L
Miami (OH)	0	2	17	62	-45	0-0	0-2	2L
Western Michigan	0	3	36	94	-58	0-1	0-2	3L