Lille vs Lyon Prediction, Betting Tips, Lineups & Odds | 28 Sep 2025

Ligue 1 Betting Preview: Lille vs Lyon

Lille host Lyon in this French Ligue 1 meeting at Stade Pierre-Mauroy, with kick-off set for 23:15 on Sunday 28 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Best Bet Could Be Backing Over 2.5

We think there’s a good angle when it comes to Over 2.5 for the clash between Lille and Lyon. Our opinion is that the Total Goals market affords great value and we will snap up the 1.71 on offer.

On board with our big-score prediction? Lock in the Stake promo code and read our comprehensive review before placing your bet.

Lyon Won 2-1 in Teams’ Previous H2H

LOSC Lille have landed back-to-back Ligue 1 home victories. In their last league game, it was a 3-0 road defeat against RC Lens at Stade Bollaert-Delelis. Bruno Genesio's team had the majority of the ball enjoying 62% possession and three shots on target.

On Thursday night, Lille secured a 2-1 Europa League victory at home to Brann.

Lyon won their previous Ligue 1 game, beating Angers at home. It was a 1-0 win at Parc Olympique Lyonnais. The Auvergne-Rhône-Alpes club enjoyed 67% possession and managed five shots on goal, with Tanner Tessmann scoring the winner in the 65th minute.

Last time out, Lyon claimed a 1-0 victory when facing FC Utrecht away in the Europa League.

Head-to-Head Statistics

Lyon haven’t lost to Lille in their past four games. Their last encounter saw Lyon make home advantage count at Parc Olympique Lyonnais, winning 2-1. The past 10 H2H games have featured four triumphs for Lyon, two for Lille and four draws.

Ligue 1		G	W	D	L	GF	GA	GD	GD	P
4	Lyon	5	4	0	1	7	3	4	7:3	12
6	Lille	5	3	1	1	13	8	5	13:8	10

View Full Table

6 wins, 2 losses and 2 draws, averaging 2.1 goals from 4.8 shots on goal and 14.6 attempts. Lille have had 59.6% possession, 522.5 passes and 6.4 corners per game. On average, they have conceded 1.3 goals from 3.5 shots on goal and 9.4 attempts, while the opposition have been awarded 4.0 corners.

Top scorers are Matias Fernandez-Pardo and Hakon Arnar Haraldsson on 3 goals, while Hamza Igamane has racked up 2. Felix Correia is the leading assists maker with 3, while goalkeepers Berke Ozer and Lucas Chevalier collectively have 2 clean sheets.

Lyon have won 6 and lost 4, with an average of 1.5 goals from 14.1 attempts and 4.6 shots on goal. Paulo Fonseca's team average 56.4% possession, 469.9 passes, 6.6 corners awarded and 5.2 corners against them, while conceding 1.0 goals from 12.6 attempts and 3.7 shots on goal.

Corentin Tolisso, Georges Mikautadze and Alexandre Lacazette have scored 3 goals, followed by Tanner Tessmann with 2. Ainsley Maitland-Niles leads the way with 3 assists, while Remy Descamps, Lucas Perri and Dominik Greif have notched 5 clean sheets between them in the previous 10 games.

Predicted & Confirmed Lineups

Lille predicted lineup (4-2-3-1): Berke Ozer (GK), Aissa Mandi, Nathan Ngoy, Chancel Mbemba, Romain Perraud, Nabil Bentaleb, Ayyoub Bouaddi, Matias Fernandez-Pardo, Hakon Arnar Haraldsson, Felix Correia, Olivier Giroud.

Lyon predicted lineup (4-2-3-1): Dominik Greif (GK), Ainsley Maitland-Niles, Clinton Mata, Moussa Niakhate, Nicolas Tagliafico, Tanner Tessmann, Corentin Tolisso, Khalis Merah, Adam Karabec, Malick Fofana, Martin Satriano.

Lille vs Lyon Prediction & Betting Tips

Be ready for Lille vs Lyon with our in-depth betting tips, featuring a key match prediction, our expected scoreline, best corners advice, player props to watch and a value-focused bet builder.

Match Prediction

This upcoming encounter could yield Over 2.5 Goals and we’re keen to back this Ligue 1 prediction. There is plenty of value when it comes betting this selection at odds of 1.71.

The form guide is always considered and it’s great to also use the Ligue 1 team news as it filters through ahead of kick-off. In our quest for the best possible football predictions, the latest stats are scrutinised so that we have the best data.

Key Lille vs Lyon league stats:

• The 2.5 line has been covered in 4 of the last 5 Lille games.
• The 2.5 line has been covered in 11 of the last 18 Lille games at home.
• The 2.5 line has been covered in the last 3 Lille games.
• The 2.5 line has been covered in 14 of the last 20 OL games.
• The 2.5 line has been covered in 11 of the last 18 OL games on the road.

Over 2.5 Probability

The betting odds at the top bookies suggest our pick carries a 58.5% chance of winning. In our opinion, there’s actually a probability of success between 65-70%. This is why we regard this as a value wager.

There are alternatives to this betting selection including Over 3.5 Goals where bettors can land bigger odds. You need four or more to be scored in order to trigger a pay out with this pick.

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Our Match Prediction

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Correct Score Prediction

Lille 2 - 1 Lyon

An exciting bet could be a 2-1 victory in favor of Lille at odds of 8.00. A correct score wager provides a fun alternative and a nice potential return on the cards.

Player Prop Picks

Corners Prediction

Over 9.5 Corners

It’s been four straight Lille games where the 9.5 Total Corners line has been covered, while we’ve seen an average of 12.20 corners in the previous five Lyon matches. If you agree with our verdict that the Total Corners line can be covered, then you can land odds of 1.68 that this happens.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Lille

Total

10.40 6.40 4.00

Home

10.50 6.40 4.10

Away

9.20 5.00 4.20

Lyon

Total

11.80 6.60 5.20

Home

9.10 5.50 3.60

Away

11.40 5.00 6.40

Latest Corner Odds

Total Corners

Lille Corners

Lyon Corners

Most Corners

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Lille vs Lyon Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Lille Full-Time Odds Suggest Victory

The bookies have LOSC Lille at 2.23 when it comes to Full-Time Result. This implies that the favourites are 45% likely to win this Ligue 1 encounter according to the latest betting odds. Lyon are trading at a bigger price than their opponents and the outsiders can be backed at 3.00.

There are different betting angles when backing Lille including the Asian Handicap -0.25 wager. This is available at 1.92 and there’s a half stake return if they only draw with Lyon.

Over 2.5 Goals is available at shorter odds than Under 2.5 Goals as things stand. An alternative angle is a Both Teams to Score bet and Yes has been chalked up at 1.58.

The best football betting sites have excellent coverage for the latest Ligue 1 games. They supply customers with hundreds of markets and it’s down to you to find the best angle.

Olivier Giroud Favourite to Be First Goalscorer

Those interested in Olivier Giroud to find the net anytime can get 2.43, with the favourite on offer to score the first goal at odds of 5.00.

Can Lille Land Yet Another Home Win?

Lille have racked up four consecutive victories at Stade Pierre-Mauroy. Bruno Genesio's side have clocked up eight wins, one draw and one defeat in the past 10 home games, recording an average of 1.60 goals per match and conceding 0.80.

Lyon have recorded five defeats, four victories and one draw in the previous 10 away matches, netting an average of 1.70 goals per game and conceding 1.70.

It was a 1-1 draw when Lille last faced Lyon at Stade Pierre-Mauroy. The past 6 H2H games at Stade Pierre-Mauroy have resulted in four draws along with a win for Lille and Lyon.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Lille Home Stats		8-1-1	2.40	1.60	0.80	6	4	7	3
Lyon Away Stats		4-1-5	3.40	1.70	1.70	6	4	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Lille vs Lyon Lineups & Team News

Be prepared — check the Lille vs OL team news before wagering. We’ll have the predicted and confirmed Ligue 1 lineups for you plus all the latest on player injuries.

LOSC Lille Team Page Olympique Lyonnais Team Page